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Clinical Trials

Recruiting Patients

RPGR

STATUS OF TRIAL

Recruiting

Gene Therapy Trial, due to RPGR

BRIEF DESCRIPTION

Gene Therapy Trial for the Treatment of XLRP Associated With Variants in the RPGR Gene. ClinicalTrials.gov Identifier: NCT04671433

INTERVENTION 

Biological: Genetic: AAV5-RPGR

STUDY RESULTS

No Results Available

Gene Therapy Trial, due to RPGR

INSTITUTION

Aaron Los Nagiel, Vitreol Retinal Assoc, Emory Eye Centre, Mass Eye & Ear, Univ of MI, Retinal Cons of Houston

LOCATION

USA

RPGR

STATUS OF TRIAL

Recruiting

Natural History Study With Mutations in RPGR

BRIEF DESCRIPTION

Natural History Study of Patients With X-linked Retinal Dystrophy Associated With Mutations in Retinitis Pigmentosa GTPase Regulator (RPGR)

INTERVENTION 

STUDY RESULTS

No Results Available

Natural History Study With Mutations in RPGR

INSTITUTION

Shiley Eye Inst, Emory Eye Ctr, Mass Eye & Ear Infirmary, Kellogg Eye Ctr, UPMC Eye Ctr, Hosp for Sick Children, Moorfields Eye Hosp

LOCATION

USA, Canada UK

RPGR

STATUS OF TRIAL

Recruiting

Follow-Up Gene Therapy Study - RPGR

BRIEF DESCRIPTION

Long Term Follow-Up Gene Therapy Study for XLRP RPGR

INTERVENTION 

Biological: AAV-RPGR

STUDY RESULTS

No Results Available

Follow-Up Gene Therapy Study - RPGR

INSTITUTION

Moorfields Eye Hospital

LOCATION

London, UK

RPGR

STATUS OF TRIAL

Recruiting

Safety/Efficacy of rAAV2tYF-GRK1- RPGR Mutations

BRIEF DESCRIPTION

Safety and Efficacy of rAAV2tYF-GRK1-RPGR in Subjects With X-linked Retinitis Pigmentosa Caused by RPGR Mutations

INTERVENTION 

Biological: rAAV2tYF-GRK1-RPGR

STUDY RESULTS

No Results Available

Safety/Efficacy of rAAV2tYF-GRK1- RPGR Mutations

INSTITUTION

Univ of FL, Boston Children's Hosp, Columbia Univ, Duke Eye Ctr, Cincinnati Eye Inst, Casey Eye Inst, Oregon Health & Science, Retina Found of SW

LOCATION

FL, MA, NY, NC, OH, OR, TX (USA)

RPGR

STATUS OF TRIAL

Recruiting

Gene Therapy Trial - Variants in RPGR

BRIEF DESCRIPTION

Follow-up Gene Therapy Trial for the Treatment of XLRP Associated With Variants in the RPGR Gene. ClinicalTrials.gov Identifier: NCT04794101

INTERVENTION 

Biological: Genetic: AAV5-RPGR 4e11|Biological: Genetic: AAV5-RPGR 2e11

STUDY RESULTS

No Results Available

Gene Therapy Trial - Variants in RPGR

INSTITUTION

Children's Hosp LA, Vitreo Retinal Assoc, Emory Eye Ctr, Boston Eye & Ear, Univ of MI Retinal Cons of Houston

LOCATION

USA

RPE65

STATUS OF TRIAL

Recruiting

Natural History IRD due to RPE65

BRIEF DESCRIPTION

Natural History of Patients With Inherited Retinal Diseases Due to Mutations in RPE65 Gene

INTERVENTION 

STUDY RESULTS

No Results Available

Natural History IRD due to RPE65

INSTITUTION

UOC, AOU, IRCCS

LOCATION

Camposampiero, Florence, Milan, Naples, Rome, Pavia (Italy)

RP11

STATUS OF TRIAL

Recruiting

Natural History Study of RP11

BRIEF DESCRIPTION

Natural History Study of Retinitis Pigmentosa Type 11

INTERVENTION 

Diagnostic Test: Clinical examinations

STUDY RESULTS

No Results Available

Natural History Study of RP11

INSTITUTION

Dept of Ophthalmology, Oslo Univ Hospital

LOCATION

Oslo, Norway

RLBP1

STATUS OF TRIAL

Recruiting

Proof of Concept Study, CPK850 for RLBP1

BRIEF DESCRIPTION

A First-in-human, Proof of Concept Study of CPK850 in Patients With RLBP1 Retinitis Pigmentosa

INTERVENTION 

Biological: CPK850

STUDY RESULTS

No Results Available

Proof of Concept Study, CPK850 for RLBP1

INSTITUTION

Novartis Investigative Site

LOCATION

Stockholm, Sweden

RHO

STATUS OF TRIAL

Recruiting

HCQ for RP due to P23H Mutation

BRIEF DESCRIPTION

Oral Hydroxychloroquine (HCQ) for Retinitis Pigmentosa Caused by P23H- Rhodopsin (RHO)

INTERVENTION 

Drug: Hydroxychloroquine lower dose|Drug: Hydroxychloroquine higher dose

STUDY RESULTS

No Results Available

HCQ for RP due to P23H Mutation

INSTITUTION

University of Michigan

LOCATION

Ann Arbor, MI, USA

RHO

STATUS OF TRIAL

Recruiting

QR-1123 in Subjects With RP Due to P23H Mutation in RHO

BRIEF DESCRIPTION

A Study to Evaluate the Safety and Tolerability of QR-1123 in Subjects With Autosomal Dominant Retinitis Pigmentosa Due to the P23H Mutation in the RHO Gene

INTERVENTION 

Drug: QR-1123|Other: Sham procedure

STUDY RESULTS

No Results Available

QR-1123 in Subjects With RP Due to P23H Mutation in RHO

INSTITUTION

Sue Anschutz-Rogers Eye Ctr, Vitreo Retinal Assoc, Shriners UK Ophth, Casey Eye Inst, Retina Found SW

LOCATION

Colorado, Florida, Kentucky, Oregon, Texas (USA)

PDE6B

STATUS OF TRIAL

Recruiting

Safety/Efficacy Study - RP Due to PDE6B

BRIEF DESCRIPTION

Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B Gene

INTERVENTION 

Biological: AAV2/5-hPDE6B

STUDY RESULTS

No Results Available

Safety/Efficacy Study - RP Due to PDE6B

INSTITUTION

Clinique Ophtalmologique

LOCATION

Nantes, France

PDE6A

STATUS OF TRIAL

Recruiting

PDE6A Gene Therapy for RP

BRIEF DESCRIPTION

PDE6A Gene Therapy for Retinitis Pigmentosa

INTERVENTION 

Drug: subretinal injection of rAAV.hPDE6A

STUDY RESULTS

No Results Available

PDE6A Gene Therapy for RP

INSTITUTION

University Tubingen

LOCATION

Tubingen, Germany

PCDH15

STATUS OF TRIAL

Recruiting

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F

BRIEF DESCRIPTION

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F

INTERVENTION 

STUDY RESULTS

No Results Available

Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F

INSTITUTION

UCSF, Advanced Eye Care, Wilmer Eye Inst, Hosp for Sick Children, Univ of Tubingen, Haddassah Med Ctr, Radboud Univ

LOCATION

USA, Canada, Germany, Israel, Netherlands

EYS

STATUS OF TRIAL

Recruiting

Rate of Progression - EYS

BRIEF DESCRIPTION

Rate of Progression in EYS Related Retinal Degeneration

INTERVENTION 

STUDY RESULTS

No Results Available

Rate of Progression - EYS

INSTITUTION

Assoc Retina Consultants, Stanford Ophth, Shiley Eye Inst, UCSF, CO Retina Assoc, NEI, Vitreo-Retinal Assoc, U of Miami, Emory Eye Ctr, U of KY, Wilmer Eye Inst, Mass Eye & Ear, Kellogg Eye Ctr, Duke Univ Eye Ctr, Casey Eye Inst, U of Pittsburgh, Retina Found SW, McPherson Eye Res Inst, Ghent Univ Hosp, Fed U of SÌ£o Paulo, Hosp for Sick Children, Helsinki U Hosp, Ctr Hosp Natl d'Ophth, U of Tubingen, Hadassah Med Ctr, Radboud U, U of Lublin

LOCATION

USA, Belgium, Brazil, Canada, Finland, France, Germany, Netherlands, Israel, Poland

CNGB1

STATUS OF TRIAL

Recruiting

CNGB1 and Allied Disorders

BRIEF DESCRIPTION

CNGB1 and Allied Disorders

INTERVENTION 

Other: No intervention, this is a natural history progression study

STUDY RESULTS

No Results Available

CNGB1 and Allied Disorders

INSTITUTION

S. H. Tsang, Wills Eye Hosp, Institut de la Vision, LMU Klinikum, Eberhard Karls Univ, Moorfields Eye Hosp

LOCATION

USA, France, Germany, UK

STATUS OF TRIAL

Recruiting

Multimodal Ophthalmic Imaging

BRIEF DESCRIPTION

Multimodal Ophthalmic Imaging

INTERVENTION 

Device: High-resolution retinal imaging through adaptive optics|Device: High-resolution retinal imaging through holographic systems

STUDY RESULTS

No Results Available

Multimodal Ophthalmic Imaging

INSTITUTION

Centre Hospitalier National d'Ophtalmologie des 15-20

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

IRD Disease Registry

BRIEF DESCRIPTION

Inherited Retinal Degenerative Disease Registry

INTERVENTION 

STUDY RESULTS

No Results Available

IRD Disease Registry

INSTITUTION

Foundation Fighting Blindness

LOCATION

Columbia, MD, USA

STATUS OF TRIAL

Recruiting

High Resolution Retina Imaging

BRIEF DESCRIPTION

High Resolution Retina Imaging

INTERVENTION 

STUDY RESULTS

No Results Available

High Resolution Retina Imaging

INSTITUTION

H̫osp Lariboisi̬re, Ctr Hosp Nat'l d'Ophtalmologie des 15-20, H̫osp Piti̩-Salp̩tri̬re

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

Computer Aided Diagnosis from Color Fundus Photograph

BRIEF DESCRIPTION

Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph

INTERVENTION 

Diagnostic Test: Software assisted imaging diagnosis

STUDY RESULTS

No Results Available

Computer Aided Diagnosis from Color Fundus Photograph

INSTITUTION

Peking Union Med College Hosp., Chinese Academy of Med Sciences, 2nd Hosp of Hebei Med Univ, West China Hosp of Sichuan Univ, Tianjin Med Univ Eye Hosp, WMU Zhejiang Eye Hosp

LOCATION

China

STATUS OF TRIAL

Recruiting

Sildenafil for Treatment of Choroidal Ischemia

BRIEF DESCRIPTION

Sildenafil for Treatment of Choroidal Ischemia

INTERVENTION 

Drug: Sildenafil|Other: Standard of Care Sildenafil|Diagnostic Test: Ocular Coherence Tomography-Angiography (OCT-A)|Other: Visual Acuity (VA)

STUDY RESULTS

No Results Available

Sildenafil for Treatment of Choroidal Ischemia

INSTITUTION

Edward Harkness Eye Institute

LOCATION

New York, NY, USA

STATUS OF TRIAL

Recruiting

Bimodal & Coaxial High Res Ophthalmic Imaging

BRIEF DESCRIPTION

Bimodal and Coaxial High Resolution Ophthalmic Imaging

INTERVENTION 

Other: Bimodal high resolution imaging of the retina

STUDY RESULTS

No Results Available

Bimodal & Coaxial High Res Ophthalmic Imaging

INSTITUTION

Centre Hospitalier National d'Ophtalmologie des 15-20

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

Stem Cell Ophthalmology Treatment Study II

BRIEF DESCRIPTION

Stem Cell Ophthalmology Treatment Study II

INTERVENTION 

Procedure: Arm 1|Procedure: Arm 2|Procedure: Arm 3

STUDY RESULTS

No Results Available

Stem Cell Ophthalmology Treatment Study II

INSTITUTION

MD Stem Cells, MD Stem Cells, Medicare Orthopedics & Spine Hospital

LOCATION

USA & UAE

STATUS OF TRIAL

Recruiting

Visual Performance Measures to Assess Clinical Trial Outcomes

BRIEF DESCRIPTION

Visual Performance Measures in a Virtual Reality Environment for Assessing Clinical Trial Outcomes in Those With Severely Reduced Vision

INTERVENTION 

Device: Virtual Reality Headset based tests

STUDY RESULTS

No Results Available

Visual Performance Measures to Assess Clinical Trial Outcomes

INSTITUTION

NI Clinical Research Facility

LOCATION

Belfast, Northern Ireland, UK

STATUS OF TRIAL

Recruiting

BS01 in Patients With RP

BRIEF DESCRIPTION

BS01 in Patients With Retinitis Pigmentosa

INTERVENTION 

Drug: BS01

STUDY RESULTS

No Results Available

BS01 in Patients With RP

INSTITUTION

OCLI

LOCATION

New York, NY, USA

STATUS OF TRIAL

Recruiting

Implantation of hESC - patients with Monogenic Mutation

BRIEF DESCRIPTION

Interventional Study of Implantation of hESC-derived RPE in Patients With RP Due to Monogenic Mutation

INTERVENTION 

Biological: Human Embryonic Stem Cell Derived Retinal Pigment Epithelium (RPE)

STUDY RESULTS

No Results Available

Implantation of hESC - patients with Monogenic Mutation

INSTITUTION

Centre Hospitalier National d'Ophtalmologie (CHNO) des Quinze-Vingts, Paris, France

LOCATION

Centre Hospitalier National d'Ophtalmologie (CHNO) des Quinze-Vingts, Paris, France

STATUS OF TRIAL

Recruiting

Rod and Cone Mediated Function in Retinal Disease

BRIEF DESCRIPTION

Rod and Cone Mediated Function in Retinal Disease

INTERVENTION 

Device: Medmont Darl Adapted Chromatic (DAC)|Device: RetMap, RM Electrode|Device: MonCvONE electrophysiology

STUDY RESULTS

No Results Available

Rod and Cone Mediated Function in Retinal Disease

INSTITUTION

National Institutes of Health Clinical Center

LOCATION

Bethesda, MD, USA

STATUS OF TRIAL

Recruiting

UMSCs for the Management of RP (RP)

BRIEF DESCRIPTION

Investigation of Therapeutic Efficacy and Safety of UMSCs for the Management of Retinitis Pigmentosa (RP)

INTERVENTION 

Biological: Injection of stem cells in sub-tenon space of eye for the management of retinitis pigmentosa|Biological: Injection of stem cells in suprachoroidal space of eye for the management of Retinitis Pigmentosa

STUDY RESULTS

No Results Available

UMSCs for the Management of RP (RP)

INSTITUTION

Stem Cell Lab, Jinnah Burn & Reconstructive Surgery Centre

LOCATION

Punjab, Pakistan

STATUS OF TRIAL

Recruiting

CB-PRP in RP

BRIEF DESCRIPTION

CB-PRP in Retinitis Pigmentosa

INTERVENTION 

Biological: Subretinal injection of umbilical cord blood platelet-rich plasma (CB-PRP)

STUDY RESULTS

No Results Available

CB-PRP in RP

INSTITUTION

Alfonso Savastano

LOCATION

Rome, Italy

STATUS OF TRIAL

Recruiting

Growing-up With Rare Genetic Syndromes

BRIEF DESCRIPTION

GROWing Up With Rare GENEtic Syndromes

INTERVENTION 

Diagnostic Test: Retrospective file studies

STUDY RESULTS

No Results Available

Growing-up With Rare Genetic Syndromes

INSTITUTION

Erasmus Medical Center, Rotterdam, Zuid-Holland, Netherlands

LOCATION

Erasmus Medical Center, Rotterdam, Zuid-Holland, Netherlands

STATUS OF TRIAL

Recruiting

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

BRIEF DESCRIPTION

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

INTERVENTION 

STUDY RESULTS

No Results Available

Evaluation of Objective Perimetry Using Chromatic Multifocal Pupillometer

INSTITUTION

Sheba Medical Center

LOCATION

Tel HaShomer, Israel

STATUS OF TRIAL

Recruiting

Impact of Visual Field Restriction on Visual Exploration

BRIEF DESCRIPTION

Impact of Visual Field Restriction on Visual Exploration

INTERVENTION 

Other: Eye tracker

STUDY RESULTS

No Results Available

Impact of Visual Field Restriction on Visual Exploration

INSTITUTION

Paris, France

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

Prospective Natural History Study of RP

BRIEF DESCRIPTION

Prospective Natural History Study of Retinitis Pigmentosa

INTERVENTION 

Other: Ophthalmic examination|Other: Mobility Test

STUDY RESULTS

No Results Available

Prospective Natural History Study of RP

INSTITUTION

CHNO XV-XX Paris

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

Effect of Oral Admin 9-cis

BRIEF DESCRIPTION

The Effect of Oral Administration of 9-cis, Carotene Rich Powder of the Alga Dunaliella Bardawil

INTERVENTION 

Dietary Supplement: Alga Dunaliella Bardawil|Other: Placebo (starch)

STUDY RESULTS

No Results Available

Effect of Oral Admin 9-cis

INSTITUTION

Sheba Medical Center

LOCATION

Tel Hashomer, Israel

STATUS OF TRIAL

Recruiting

Dose-escalation Study - Safety & Tolerability of GS030

BRIEF DESCRIPTION

Dose-escalation Study to Evaluate the Safety and Tolerability of GS030 in Subjects With Retinitis Pigmentosa

INTERVENTION 

Combination Product: Gene therapy: GS030-DP AND Medical device: GS030-MD

STUDY RESULTS

No Results Available

Dose-escalation Study - Safety & Tolerability of GS030

INSTITUTION

UPMC Eye Center, CHNP, Moorfields Eye Hospital

LOCATION

USA, France, UK

STATUS OF TRIAL

Recruiting

Cell Collection to Study Eye Diseases

BRIEF DESCRIPTION

Cell Collection to Study Eye Diseases

INTERVENTION 

STUDY RESULTS

No Results Available

Cell Collection to Study Eye Diseases

INSTITUTION

NIH Clinical Center

LOCATION

Bethesda, MD, USA

STATUS OF TRIAL

Recruiting

Subretinal Trans of Stem Cell Derived Retinal Pigment Epitheliums

BRIEF DESCRIPTION

Safety and Efficacy of Subretinal Transplantation of Clinical Human Embryonic Stem Cell Derived Retinal Pigment Epitheliums in Treatment of Retinitis Pigmentosa

INTERVENTION 

Biological: Retinal pigment epitheliums transplantation

STUDY RESULTS

No Results Available

Subretinal Trans of Stem Cell Derived Retinal Pigment Epitheliums

INSTITUTION

Beijing Tongren Hosp, Capital Med Univ

LOCATION

Beijing, China

STATUS OF TRIAL

Recruiting

Dev of iPS from Donated Somatic Cells

BRIEF DESCRIPTION

Development of iPS From Donated Somatic Cells of Patients With Neurological Diseases

INTERVENTION 

STUDY RESULTS

No Results Available

Dev of iPS from Donated Somatic Cells

INSTITUTION

Hadassah Ein Kerem

LOCATION

Jerusalem, Israel

STATUS OF TRIAL

Recruiting

Pilot Study of Intravitreal Autologous CD34+ Stem Cell Therapy for RP

BRIEF DESCRIPTION

Pilot Study of Intravitreal Autologous CD34+ Stem Cell Therapy for Retinitis Pigmentosa

INTERVENTION 

Biological: Intravitreal autologous CD34+ cells

STUDY RESULTS

No Results Available

Pilot Study of Intravitreal Autologous CD34+ Stem Cell Therapy for RP

INSTITUTION

UC Davis

LOCATION

Davis, CA, USA

STATUS OF TRIAL

Recruiting

Validation of Standardized Test Protocols - Daily Life Activities

BRIEF DESCRIPTION

Validation of Standardized Test Protocols to Assess the Impact of Visual Pathologies in Daily Life Activities

INTERVENTION 

Behavioral: performance of behavioral locomotion tasks phase 1|Behavioral: performance of behavioral locomotion tasks phase 2

STUDY RESULTS

No Results Available

Validation of Standardized Test Protocols - Daily Life Activities

INSTITUTION

Centre Hospitalier National d'Ophtalmologique

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

Environmental Localization Mapping and Guidance for Visual Prosthesis Users

BRIEF DESCRIPTION

Environmental Localization Mapping and Guidance for Visual Prosthesis Users

INTERVENTION 

Device: Navigation System for Users of a Visual Prosthesis

STUDY RESULTS

No Results Available

Environmental Localization Mapping and Guidance for Visual Prosthesis Users

INSTITUTION

Wilmer Eye Inst & Johns Hopkins Applied Physics Laboratory

LOCATION

Baltimore, MD, USA

STATUS OF TRIAL

Recruiting

Natural History - Progression of XLRP

BRIEF DESCRIPTION

Natural History of the Progression of X-Linked Retinitis Pigmentosa

INTERVENTION 

Other: Other: Assessments

STUDY RESULTS

No Results Available

Natural History - Progression of XLRP

INSTITUTION

Multiple research sites

LOCATION

USA, Canada, Finland, Germany, Netherlands, United Kingdom

STATUS OF TRIAL

Recruiting

Minocycline Treatment in RP

BRIEF DESCRIPTION

Minocycline Treatment in Retinitis Pigmentosa

INTERVENTION 

Drug: Minocycline

STUDY RESULTS

No Results Available

Minocycline Treatment in RP

INSTITUTION

Zhongshan Ophthalmic Center, Sun Yat-sen University

LOCATION

Guangdong, China

STATUS OF TRIAL

Recruiting

CNS10-NPC - Treatment of RP

BRIEF DESCRIPTION

CNS10-NPC for the Treatment of RP

INTERVENTION 

Biological: CNS10-NPC implantation

STUDY RESULTS

No Results Available

CNS10-NPC - Treatment of RP

INSTITUTION

Retina-Vitreous Assoc Med Group

LOCATION

Beverly Hills, CA, USA

STATUS OF TRIAL

Recruiting

UAB HRFD Core Center: Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource

BRIEF DESCRIPTION

UAB HRFD Core Center: Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource

INTERVENTION 

STUDY RESULTS

No Results Available

UAB HRFD Core Center: Core A: The Hepato/Renal Fibrocystic Diseases Translational Resource

INSTITUTION

Children's National Health System

LOCATION

Washington, D.C., USA

STATUS OF TRIAL

Recruiting

4D-125 in Patients with XLRP

BRIEF DESCRIPTION

4D-125 in Patients With X-Linked Retinitis Pigmentosa (XLRP)

INTERVENTION 

Biological: 4D-125 IVT Injection|Other: Observational

STUDY RESULTS

No Results Available

4D-125 in Patients with XLRP

INSTITUTION

Univ of CO, Kellogg Eye Ctr, Duke Univ Eye Ctr, Casey Eye Inst, Retina Found of SW, John A. Moran Eye Ctr

LOCATION

USA

STATUS OF TRIAL

Recruiting

Safety and Tolerability of hRPC

BRIEF DESCRIPTION

Safety and Tolerability of hRPC in Retinitis Pigmentosa

INTERVENTION 

Drug: hRPC

STUDY RESULTS

No Results Available

Safety and Tolerability of hRPC

INSTITUTION

Retinal Research Inst, Mass Eye & Ear Infirmary, Oregon Health & Sci Univ, Inst de la Macula, Oxford Eye Hosp

LOCATION

USA, Spain, UK

STATUS OF TRIAL

Recruiting

Clinical Eval - Patients With XLRP

BRIEF DESCRIPTION

Clinical Evaluation of Patients With X-linked Retinitis Pigmentosa (XLRP)

INTERVENTION 

STUDY RESULTS

No Results Available

Clinical Eval - Patients With XLRP

INSTITUTION

Duke Eye Center, Casey Eye Institute, Retina Foundation of SW

LOCATION

NC, OR, TX (USA)

STATUS OF TRIAL

Recruiting

High Resolution Retinal Imaging

BRIEF DESCRIPTION

High Resolution Retinal Imaging

INTERVENTION 

STUDY RESULTS

No Results Available

High Resolution Retinal Imaging

INSTITUTION

University of Pennsylvania

LOCATION

Philadelphia, PA, USA

STATUS OF TRIAL

Recruiting

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

BRIEF DESCRIPTION

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

INTERVENTION 

STUDY RESULTS

No Results Available

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford

INSTITUTION

Sanford Health, Online Patient Enrollment System

LOCATION

USA, Australia

STATUS OF TRIAL

Recruiting

NR600 System Retinal Prosthesis for Patients With Retinal Degenerative Diseases

BRIEF DESCRIPTION

NR600 System Retinal Prosthesis for Patients With Retinal Degenerative Diseases

INTERVENTION 

Device: Retinal surgery with implantation of epi-retinal device

STUDY RESULTS

No Results Available

NR600 System Retinal Prosthesis for Patients With Retinal Degenerative Diseases

INSTITUTION

UZ Ghent, UZ Leuven, Rabin Med Ctr, Sourasky Med Ctr, Fondazione Policlinico A. Gemelli

LOCATION

Belgium, Israel, Italy

STATUS OF TRIAL

Recruiting

RP Clinical Measures - Repeatability Testing- Potential Outcome Measures

BRIEF DESCRIPTION

Retinitis Pigmentosa Clinical Measures and Repeatability Testing of Potential Outcome Measures

INTERVENTION 

STUDY RESULTS

No Results Available

RP Clinical Measures - Repeatability Testing- Potential Outcome Measures

INSTITUTION

NIH Clinical Center

LOCATION

Bethesda, MD, USA

STATUS OF TRIAL

Recruiting

Experimental & Clinical Studies, Retinal Stimulation

BRIEF DESCRIPTION

Experimental and Clinical Studies of Retinal Stimulation

INTERVENTION 

Device: New visual processing unit (VPU) with asymmetric waveforms|Device: New VPU with bipolar stimulation

STUDY RESULTS

No Results Available

Experimental & Clinical Studies, Retinal Stimulation

INSTITUTION

University of Michigan

LOCATION

Ann Arbor, Michigan, USA

STATUS OF TRIAL

Recruiting

Func & Anatomical Progression in RP

BRIEF DESCRIPTION

A Natural History Study to Evaluate Functional and Anatomical Progression in Retinitis Pigmentosa

INTERVENTION 

STUDY RESULTS

No Results Available

Func & Anatomical Progression in RP

INSTITUTION

Wilmer Eye Institute, Johns Hopkins Univ

LOCATION

Baltimore, MD, USA

STATUS OF TRIAL

Recruiting

Retinal Imaging - IRD

BRIEF DESCRIPTION

Retinal Imaging in Patients With Inherited Retinal Degenerations

INTERVENTION 

STUDY RESULTS

No Results Available

Retinal Imaging - IRD

INSTITUTION

Dept of Ophth Retinal Degenerations Clinic, UCSF

LOCATION

SF, California, USA

STATUS OF TRIAL

Recruiting

Effects of Cannabis - Visual Functions

BRIEF DESCRIPTION

The Effects of Cannabis on Visual Functions in Healthy and Retinitis Pigmentosa Patients

INTERVENTION 

Drug: cannabis

STUDY RESULTS

No Results Available

Effects of Cannabis - Visual Functions

INSTITUTION

Hadassah Medical Center

LOCATION

Jerusalem, Israel

STATUS OF TRIAL

Recruiting

Retrospective NIS - Benefit of TES

BRIEF DESCRIPTION

Retrospective NIS to Evaluate the Patient Benefit of TES

INTERVENTION 

Device: Transcorneal Electrostimulation via OkuStim System

STUDY RESULTS

No Results Available

Retrospective NIS - Benefit of TES

INSTITUTION

Univ Augenklinik Tübingen

LOCATION

Tübingen, Germany

STATUS OF TRIAL

Recruiting

Phenotype Correlates Genotype of Inherited Retina Dystrophies, RP, Con>Rod Dystrophies.

BRIEF DESCRIPTION

Phenotype Correlates Genotype of Inherited Retina Dystrophies, Retinitis Pigmentosa, Con>Rod Dystrophies.

INTERVENTION 

Diagnostic Test: Retina Analysis-mosaic|Diagnostic Test: Autofluorescence|Diagnostic Test: OCT- 1 micra|Procedure: Genotype analysis

STUDY RESULTS

No Results Available

Phenotype Correlates Genotype of Inherited Retina Dystrophies, RP, Con>Rod Dystrophies.

INSTITUTION

Retina & Genomics Institute

LOCATION

Merida, Yucatan, Mexico

STATUS OF TRIAL

Recruiting

Mobility Protocol - Advanced Visually Impaired Subjects

BRIEF DESCRIPTION

Mobility Protocol Adapted for Advanced Visually Impaired Subjects

INTERVENTION 

Behavioral: Locomotion task|Behavioral: Posturology task SOT (Sensory Organization Test)|Behavioral: The quality of life questionnaire

STUDY RESULTS

No Results Available

Mobility Protocol - Advanced Visually Impaired Subjects

INSTITUTION

Centre Hospitalier National d'Ophtalmologie des 15-20

LOCATION

Paris, France

STATUS OF TRIAL

Recruiting

Efficacy/Safety - Optogenetic Therapy in Adults

BRIEF DESCRIPTION

Efficacy and Safety of of vMCO-010 Optogenetic Therapy in Adults With Retinitis Pigmentosa [RESTORE]

INTERVENTION 

Biological: Gene Therapy Product-vMCO-010|Procedure: Sham Injection

STUDY RESULTS

No Results Available

Efficacy/Safety - Optogenetic Therapy in Adults

INSTITUTION

Nanoscope Clinical Site

LOCATION

USA, Puerto Rico

STATUS OF TRIAL

Recruiting

Argus II/ORCAM Device Study

BRIEF DESCRIPTION

Argus II/ORCAM Device Study

INTERVENTION 

Device: Argus II Eyeglasses|Device: ORCAM

STUDY RESULTS

No Results Available

Argus II/ORCAM Device Study

INSTITUTION

Mayo Clinic

LOCATION

Rochester, Minnesota, USA

STATUS OF TRIAL

Recruiting

Study - Japanese Participants with XLRP

BRIEF DESCRIPTION

An Observational Study of Japanese Participants With X-linked Retinitis Pigmentosa

INTERVENTION 

STUDY RESULTS

No Results Available

Study - Japanese Participants with XLRP

INSTITUTION

Natl Hosp Org Tokyo Med Ctr

LOCATION

Tokyo, Japan

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